WordFence, Better WP Security, Login Security Solution
These plugins block access to your site’s XML-RPC file. This file is used by Jetpack to connect to WordPress.com, and must be accessible at all times. You will consequently need to deactivate these plugins to be able to use Jetpack.
W3 Total Cache
There are known issues with the Minify engine in W3 Total Cache and many other plugins, including Jetpack. For now, you will need to turn off the Minify engine in W3TC to get Jetpack fully functional.
Simple Facebook Connect
Jetpack’s Contact Form module currently is not working correctly with Simple Facebook Connect or other plugins that call the ‘the_content’ filter in several places. This is a known bug we are working on fixing.
During the Jetpack connection process, BuddyPress may redirect you to your homepage instead of through the appropriate pages necessary to create a connection. Disable BuddyPress before connecting Jetpack.
It’s currently not possible to use Jetpack’s Comment module if you have previously activated the Antispam Bee plugin. You will have to disable this plugin if you want to use Jetpack Comments.
Spam Free WordPress
The Spam Free WordPress plugin is currently not compatible with Jetpack Comments.
You may run into issues when submitting comments when both “Bad Behavior” and Jetpack Comments are active.
You currently cannot use Jetpack Tiled Galleries when the Events Manager plugin is active on your site.
Cleaner Gallery / Hybrid themes
If you use the Cleaner Gallery plugin or a theme including this functionality, you won’t able to use the Carousel features on your site.
The ComicPress theme is not compatible with Jetpack’s Mobile theme. Comics published via ComicPress cannot be accessed from the Mobile Theme.
CloudFlare is currently not compatible with Jetpack Likes. Like buttons won’t load until you disable CloudFlare.
Google Pagespeed may cause several issues with Jetpack Comments, Likes, and other Jetpack modules.
There are various themes available that hide the Jetpack connection window. If you install Jetpack and do not see a connection button, try changing your theme to the default WordPress theme before connecting Jetpack.